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1

Placental Growth Factor (PlGF) and Its Receptor Flt-1 (VEGFR-1) : Novel Therapeutic Targets for Angiogenic Disorders

AERNOUT LUTTUN, MARC TJWA, PETER CARMELIET

Journal:

Annals of the New York Academy of Sciences

Année:

2002

Fichier:

PDF, 3.47 MB

2002

2

Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties

Bono, Françoise, De Smet, Frederik, Herbert, Corentin, De Bock, Katrien, Georgiadou, Maria, Fons, Pierre, Tjwa, Marc, Alcouffe, Chantal, Ny, Annelii, Bianciotto, Marc, Jonckx, Bart, Murakami, Masahiro

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 795 KB

english, 2013

3

Long-term diabetes impairs repopulation of hematopoietic progenitor cells and dysregulates the cytokine expression in the bone marrow microenvironment in mice

Alessia Orlandi, Emmanouil Chavakis, Florian Seeger, Marc Tjwa, Andreas M. Zeiher, Stefanie Dimmeler

Journal:

Basic Research in Cardiology

Année:

2010

Langue:

english

Fichier:

PDF, 438 KB

english, 2010

4

VEGF and PlGF: two pleiotropic growth factors with distinct roles in development and homeostasis

Marc Tjwa, Aernout Luttun, Monica Autiero, Peter Carmeliet

Journal:

Cell and Tissue Research

Année:

2003

Langue:

english

Fichier:

PDF, 189 KB

english, 2003

5

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

Luttun, Aernout, Tjwa, Marc, Moons, Lieve, Wu, Yan, Angelillo-Scherrer, Anne, Liao, Fang, Nagy, Janice A., Hooper, Andrea, Priller, Josef, De Klerck, Bert, Compernolle, Veerle, Daci, Evis, Bohlen, Pet

Journal:

Nature Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2002

6

Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Compernolle, Veerle, Brusselmans, Koen, Acker, Till, Hoet, Peter, Tjwa, Marc, Beck, Heike, Plaisance, Stéphane, Dor, Yuval, Keshet, Eli, Lupu, Florea, Nemery, Benoit, Dewerchin, Mieke, Van Veldhoven,

Journal:

Nature Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2002

7

Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?

Aernout Luttun, Monica Autiero, Marc Tjwa, Peter Carmeliet

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 479 KB

english, 2004

8

A surrogate marker to monitor angiogenesis at last

Martin Schneider, Marc Tjwa, Peter Carmeliet

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 107 KB

english, 2005

9

Genetic evidence for a tumor suppressor role of HIF-2α

Till Acker, Antonio Diez-Juan, Julian Aragones, Marc Tjwa, Koen Brusselmans, Lieve Moons, Dai Fukumura, Maria Paz Moreno-Murciano, Jean-Marc Herbert, Angelika Burger, Johanna Riedel, Gerd Elvert, Ingo

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 878 KB

english, 2005

10

Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1+ Leukemia

Thomas Schmidt, Behzad Kharabi Masouleh, Sonja Loges, Sandra Cauwenberghs, Peter Fraisl, Christa Maes, Bart Jonckx, Kim De Keersmaecker, Maria Kleppe, Marc Tjwa, Thomas Schenk, Stefan Vinckier, Rita F

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2011

11

Fibrinolysis-independent role of plasmin and its activators in the haematopoietic recovery after myeloablation

Marc Tjwa, Rute Moura, Lieve Moons, Stephane Plaisance, Maria De Mol, Sandra Jansen, Mieke Dewerchin, Catherine Verfaillie, Peter Carmeliet

Journal:

Journal of Cellular and Molecular Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2009

12

A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span

Peter Vangheluwe, Marc Tjwa, An Van Den Bergh, William E. Louch, Monique Beullens, Leonard Dode, Peter Carmeliet, Evangelia Kranias, Paul Herijgers, Karin R. Sipido, Luc Raeymaekers, Frank Wuytack

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2006

Langue:

english

Fichier:

PDF, 577 KB

english, 2006

13

Loss of placental growth factor protects mice against vascular permeability in pathological conditions

Aernout Luttun, Koen Brusselmans, Hideharu Fukao, Marc Tjwa, Shigeru Ueshima, Jean-Marc Herbert, Osamu Matsuo, Désiré Collen, Peter Carmeliet, Lieve Moons

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 331 KB

english, 2002

14

Inactivation of Smad5 in Endothelial Cells and Smooth Muscle Cells Demonstrates that Smad5 Is Required for Cardiac Homeostasis

Lieve Umans, Luk Cox, Marc Tjwa, Virginie Bito, Liesbeth Vermeire, Kjell Laperre, Karin Sipido, Lieve Moons, Danny Huylebroeck, An Zwijsen

Journal:

The American Journal of Pathology

Année:

2007

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2007

15

Tumoral and Choroidal Vascularization: Differential Cellular Mechanisms Involving Plasminogen Activator Inhibitor Type I

Maud Jost, Catherine Maillard, Julie Lecomte, Vincent Lambert, Marc Tjwa, Pierre Blaise, Maria-Luz Alvarez Gonzalez, Khalid Bajou, Silvia Blacher, Patrick Motte, Chantal Humblet, Marie Paule Defresne,

Journal:

The American Journal of Pathology

Année:

2007

Langue:

english

Fichier:

PDF, 3.12 MB

english, 2007

16

A role for TGF-beta in transforming endothelial progenitor cells into neointimal smooth muscle cells

Gian Paolo Fadini, Marc Tjwa

Journal:

Atherosclerosis

Année:

2010

Langue:

english

Fichier:

PDF, 214 KB

english, 2010

17

Induced pluripotent stem (iPS) cells and endothelial cell generation: SIRT-ainly a good idea!

Rute Moura, Gian Paolo Fadini, Marc Tjwa

Journal:

Atherosclerosis

Année:

2010

Langue:

english

Fichier:

PDF, 159 KB

english, 2010

18

Role of CO2 pneumoperitoneum-induced acidosis in CO2 pneumoperitoneum-enhanced adhesion formation in mice

Carlos Roger Molinas, Marc Tjwa, Bernard Vanacker, Maria Mercedes Binda, Osama Elkelani, Philippe Robert Koninckx

Journal:

Fertility and Sterility

Année:

2004

Langue:

english

Fichier:

PDF, 91 KB

english, 2004

19

Better Regenerative Output After Cellular Input: Healing Hearts by Combining Basic Fibroblast Factor and Cell-Based Therapy

Stefanie Dimmeler, Marc Tjwa

Journal:

Journal of the American College of Cardiology

Année:

2008

Langue:

english

Fichier:

PDF, 174 KB

english, 2008

20

Circulating Apoptotic Endothelial Cells and Apoptotic Endothelial Microparticles Independently Predict the Presence of Cardiac Allograft Vasculopathy

Neha Singh, Eline Van Craeyveld, Marc Tjwa, Agnieszka Ciarka, Jan Emmerechts, Walter Droogne, Stephanie C. Gordts, Vincent Carlier, Frank Jacobs, Steffen Fieuws, Johan Vanhaecke, Johan Van Cleemput, B

Journal:

Journal of the American College of Cardiology

Année:

2012

Langue:

english

Fichier:

PDF, 425 KB

english, 2012

21

The role of RNA interference in the developmental separation of blood and lymphatic vasculature

Gauvrit, Sébastien, Philippe, Josette, Lesage, Matthieu, Tjwa, Marc, Godin, Isabelle, Germain, Stéphane

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2014

22

Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells

Tjwa, Marc, Sidenius, Nicolai, Moura, Rute, Jansen, Sandra, Theunissen, Koen, Andolfo, Annapaola, De Mol, Maria, Dewerchin, Mieke, Moons, Lieve, Blasi, Francesco, Verfaillie, Catherine, Carmeliet, Pet

Journal:

Journal of Clinical Investigation

Année:

2009

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2009

23

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

Kaluza, David, Kroll, Jens, Gesierich, Sabine, Yao, Tso-Pang, Boon, Reinier A, Hergenreider, Eduard, Tjwa, Marc, Rössig, Lothar, Seto, Edward, Augustin, Hellmut G, Zeiher, Andreas M, Dimmeler, Stefani

Journal:

The EMBO Journal

Année:

2011

Langue:

english

Fichier:

PDF, 2.60 MB

english, 2011

24

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

Ridder, Kirsten, Sevko, Alexandra, Heide, Janina, Dams, Maria, Rupp, Anne-Kathleen, Macas, Jadranka, Starmann, Julia, Tjwa, Marc, Plate, Karl H, Sültmann, Holger, Altevogt, Peter, Umansky, Viktor, Mom

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 652 KB

english, 2015

25

uPA Deficiency Exacerbates Muscular Dystrophy in MDX Mice

Mònica Suelves, Berta Vidal, Antonio L. Serrano, Marc Tjwa, Josep Roma, Roser López-Alemany, Aernout Luttun, María Martínez de Lagrán, Maria Àngels Díaz, Mercè Jardí, Manuel Roig, Mara Dierssen, Mieke

Journal:

The Journal of Cell Biology

Année:

2007

Langue:

english

Fichier:

PDF, 3.41 MB

english, 2007

26

Pleiotropic role of growth arrest-specific gene 6 in atherosclerosis

Tjwa, Marc, Moons, Lieve, Lutgens, Esther

Journal:

Current Opinion in Lipidology

Année:

2009

Langue:

english

Fichier:

PDF, 508 KB

english, 2009

27

Osx-Cre Targets Multiple Cell Types besides Osteoblast Lineage in Postnatal Mice

Chen, Jianquan, Shi, Yu, Regan, Jenna, Karuppaiah, Kannan, Ornitz, David M., Long, Fanxin, Tjwa, Marc

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 8.04 MB

english, 2014

28

Transient Responses to NOTCH and TLX1/HOX11 Inhibition in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Rakowski, Lesley A., Lehotzky, Erica A., Chiang, Mark Y., Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

29

MicroRNA Genes Derived from Repetitive Elements and Expanded by Segmental Duplication Events in Mammalian Genomes

Yuan, Zhidong, Sun, Xiao, Liu, Hongde, Xie, Jianming, Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2011

30

Solving the Puzzle of Metastasis: The Evolution of Cell Migration in Neoplasms

Chen, Jun, Sprouffske, Kathleen, Huang, Qihong, Maley, Carlo C., Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2011

31

A 50% Reduction of Excitability but Not of Intercellular Coupling Affects Conduction Velocity Restitution and Activation Delay in the Mouse Heart

Stein, Mèra, van Veen, Toon A. B., Hauer, Richard N. W., de Bakker, Jacques M. T., van Rijen, Harold V. M., Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2011

32

Milk Lacking α-Casein Leads to Permanent Reduction in Body Size in Mice

Kolb, Andreas F., Huber, Reinhard C., Lillico, Simon G., Carlisle, Ailsa, Robinson, Claire J., Neil, Claire, Petrie, Linda, Sorensen, Dorte B., Olsson, I. Anna S., Whitelaw, C. Bruce A., Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 3.96 MB

english, 2011

33

Clusters of Conserved Beta Cell Marker Genes for Assessment of Beta Cell Phenotype

Martens, Geert A., Jiang, Lei, Hellemans, Karine H., Stangé, Geert, Heimberg, Harry, Nielsen, Finn C., Sand, Olivier, Van Helden, Jacques, Gorus, Frans K., Pipeleers, Daniel G., Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2011

34

Quantifying the Evolution of Vascular Barrier Disruption in Advanced Atherosclerosis with Semipermeant Nanoparticle Contrast Agents

Zhang, Huiying, Zhang, Lei, Myerson, Jacob, Bibee, Kristin, Scott, Michael, Allen, John, Sicard, Gregorio, Lanza, Gregory, Wickline, Samuel, Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2011

35

MicroRNA Profiling during Cardiomyocyte-Specific Differentiation of Murine Embryonic Stem Cells Based on Two Different miRNA Array Platforms

Gan, Lin, Schwengberg, Silke, Denecke, Bernd, Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 5.14 MB

english, 2011

36

Inducible Genetic Lineage Tracing of Cortical Hem Derived Cajal-Retzius Cells Reveals Novel Properties

Gu, Xiaochun, Liu, Bin, Wu, Xiaojing, Yan, Yan, Zhang, Ying, Wei, Yiquan, Pleasure, Samuel J., Zhao, Chunjie, Tjwa, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 6.23 MB

english, 2011

37

High-Resolution In-Vivo Analysis of Normal Brain Response to Cranial Irradiation

Burrell, Kelly, Hill, Richard P., Zadeh, Gelareh, Tjwa, Marc

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 789 KB

english, 2012

38

Atmospheric Oxygen Tension Slows Myoblast Proliferation via Mitochondrial Activation

Duguez, Stephanie, Duddy, William J., Gnocchi, Viola, Bowe, James, Dadgar, Sherry, Partridge, Terence A., Tjwa, Marc

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 665 KB

english, 2012

39

MicroRNA-16 Is Down-Regulated in Mutated FLT3 Expressing Murine Myeloid FDC-P1 Cells and Interacts with Pim-1

Kim, Kyu-Tae, Carroll, Adam P., Mashkani, Baratali, Cairns, Murray J., Small, Donald, Scott, Rodney J., Tjwa, Marc

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2012

40

Stem Cell Selection In Vivo Using Foamy Vectors Cures Canine Pyruvate Kinase Deficiency

Trobridge, Grant D., Beard, Brian C., Wu, Robert A., Ironside, Christina, Malik, Punam, Kiem, Hans-Peter, Tjwa, Marc

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 640 KB

english, 2012

41

Wogonin Induced Calreticulin/Annexin A1 Exposure Dictates the Immunogenicity of Cancer Cells in a PERK/AKT Dependent Manner

Yang, Yong, Li, Xian-Jing, Chen, Zhen, Zhu, Xuan-Xuan, Wang, Jing, Zhang, Lin-bo, Qiang, Lei, Ma, Yan-jun, Li, Zhi-yu, Guo, Qing-Long, You, Qi-Dong, Tjwa, Marc

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2012

42

TAK1 (MAP3K7) Signaling Regulates Hematopoietic Stem Cells through TNF-Dependent and -Independent Mechanisms

Takaesu, Giichi, Inagaki, Maiko, Takubo, Keiyo, Mishina, Yuji, Hess, Paul R., Dean, Gregg A., Yoshimura, Akihiko, Matsumoto, Kunihiro, Suda, Toshio, Ninomiya-Tsuji, Jun, Tjwa, Marc

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2012

43

Apolipoprotein(a) Inhibits In Vitro Tube Formation in Endothelial Cells: Identification of Roles for Kringle V and the Plasminogen Activation System

Liu, Lei, Boffa, Michael B., Koschinsky, Marlys L., Tjwa, Marc

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 689 KB

english, 2013

44

Co-Culture of Hematopoietic Stem/Progenitor Cells with Human Osteblasts Favours Mono/Macrophage Differentiation at the Expense of the Erythroid Lineage

Salati, Simona, Lisignoli, Gina, Manferdini, Cristina, Pennucci, Valentina, Zini, Roberta, Bianchi, Elisa, Norfo, Ruggiero, Facchini, Andrea, Ferrari, Sergio, Manfredini, Rossella, Tjwa, Marc

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 712 KB

english, 2013

45

Biological Basis of miRNA Action when Their Targets Are Located in Human Protein Coding Region

Gu, Wanjun, Wang, Xiaofei, Zhai, Chuanying, Zhou, Tong, Xie, Xueying, Tjwa, Marc

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 447 KB

english, 2013

46

In Vivo Monitoring of Angiogenesis Inhibition via Down-Regulation of Mir-21 in a VEGFR2-Luc Murine Breast Cancer Model Using Bioluminescent Imaging

Zhao, Dongliang, Tu, Yingfeng, Wan, Lin, Bu, Lihong, Huang, Tao, Sun, Xilin, Wang, Kai, Shen, Baozhong, Tjwa, Marc

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2013

47

Drosophila E-Cadherin Functions in Hematopoietic Progenitors to Maintain Multipotency and Block Differentiation

Gao, Hongjuan, Wu, Xiaorong, Fossett, Nancy, Tjwa, Marc

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 5.49 MB

english, 2013

48

Targeting Myeloid Cells to the Brain Using Non-Myeloablative Conditioning

Böttcher, Chotima, Fernández-Klett, Francisco, Gladow, Nadine, Rolfes, Simone, Priller, Josef, Tjwa, Marc

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.30 MB

english, 2013

49

An RNAi-Based Approach to Down-Regulate a Gene Family In Vivo

Kim, Jeehee, Badaloni, Aurora, Willert, Torsten, Zimber-Strobl, Ursula, Kühn, Ralf, Wurst, Wolfgang, Kieslinger, Matthias, Tjwa, Marc

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 4.21 MB

english, 2013

50

Norepinephrine Stimulates Mobilization of Endothelial Progenitor Cells after Limb Ischemia

Jiang, Qijun, Ding, Shifang, Wu, Jianxiang, Liu, Xing, Wu, Zonggui, Tjwa, Marc

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 7.31 MB

english, 2014